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01815 | CAS:50-76-0 | Actinomycin D | 放线菌素 D
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01815 Actinomycin D
Fluka for fluorescence, ≥90% (HPLC), from Streptomyces sp.
窗体底端
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货号
号 |
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您的价格
RMB |
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01815-1MG-F |
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728.91 |
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01815-10MG-F |
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2,514.33 |
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Synonym: |
Actinomycin C1, Actinomycin IV, Dactinomycin |
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CAS Number: |
50-76-0 |
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Empirical Formula (Hill Notation): |
C62H86N12O16 |
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Molecular Weight: |
1255.42 |
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Beilstein Registry Number: |
605235 |
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EC Number: |
200-063-6 |
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MDL number: |
MFCD00005033 |
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PubChem Substance ID: |
24845202 |
Description
| Biochem/physiol Actions |
An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes. |
| Other Notes |
Antineoplastic antibiotic. Inhibitor of nucleic acid synthesis (transcription and chain elongation)1 |
性质
| biological source |
from Streptomyces sp. |
| grade |
for fluorescence |
| assay |
≥90% (HPLC) |
| color |
red, powder |
| mp |
251-253 |
| storage temp. |
2-8°C |
安全性
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